Switching antipsychotic medications, early use of clozapine and outcome in first-episode schizophrenia
Leo Sher, M.D. A seminal research work, “Amisulpride and olanzapine followed by open-label treatment with clozapine in first-episode schizophrenia and schizophreniform disorder (OPTiMiSE): a three-phase switching study” has recently been published in Lancet Psychiatry (1). A large international research group led by Professor René S. Kahn examined whether switching antipsychotic medications or early use of […]
