Ten years ago

Leo Sher, M.D. Our research report, “Combined dexamethasone suppression-corticotrophin-releasing hormone stimulation test in medication-free major depression and healthy volunteers” was published 10 years ago in the December 2013 issue of the Journal of Affective Disorders (1). A combined dexamethasone suppression– corticotrophin-releasing hormone stimulation (DEX–CRH) test has been developed as a potentially sensitive measure of hypothalamic–pituitary–adrenal […]

Leo Sher, M.D. Our research work, “Testosterone levels in suicide attempters with bipolar disorder” was published 10 years ago in the October 2012 issue of the Journal of Psychiatric Research (1). We examined whether there was a relation between testosterone levels and clinical parameters in bipolar suicide attempters. Patients with a diagnosis of a bipolar […]

Leo Sher, M.D. My paper, “Teaching medical professionals and trainees about adolescent suicide prevention: five key problems” was published 10 years ago in the April-June 2012 issue of the International Journal of Adolescent Medicine and Health (1). In this article, I suggest that many health care professionals who have frequent contact with adolescents are not […]

Leo Sher, M.D. Our research report, “Decreased suicidal ideation in depressed patients with or without comorbid posttraumatic stress disorder treated with selective serotonin reuptake inhibitors: an open study” was published 10 years ago in the April 2012 issue of Psychiatry Research (1). We have examined clinical parameters before and after three months of open selective […]

Leo Sher, M.D. Our research report, “Treatment of suicide attempters with bipolar disorder: a randomized clinical trial comparing lithium and valproate in the prevention of suicidal behavior” was published in the October 2011 issue of the American Journal of Psychiatry (1). In our double-blind, randomized, parallel-group study, we tested the hypothesis that lithium offers bipolar […]

Leo Sher, M.D. Our theoretical work, “Posttraumatic stress disorder in war veterans: a discussion of the Neuroevolutionary Time-depth Principle” was published 10 years ago in the September 2010 issue of the Journal of Affective Disorders (1). The “Neuroevolutionary Time-depth Principle” of innate fears suggests that high rates of posttraumatic stress disorder (PTSD) after combat exposure […]

Leo Sher, M.D. Our research work, “Non-suicidal self-injurious behavior, endogenous opioids and monoamine neurotransmitters” was published 10 years ago in the July 2010 issue of the Journal of Affective Disorders (1). The objective of the study was to examine the role of endogenous opioids and monoamine neurotransmitters in non-suicidal self-injury (NSSI). We compared cerebrospinal fluid […]

Leo Sher, M.D. A research article, “The impact of epidemic outbreak: the case of severe acute respiratory syndrome (SARS) and suicide among older adults in Hong Kong” was published 10 years ago in Crisis – The Journal of Crisis Intervention and Suicide Prevention (1). There was a significant increase in suicide deaths among those aged […]

Leo Sher, M.D. Our research article, “Objections to suicide among depressed patients with alcohol use disorders” was published 10 years ago in the October 2009 issue of the Journal of Affective Disorders (1). In all, 521 mood disordered patients with and without alcohol use disorders were administered a battery of clinical measures including the Scale […]

Leo Sher, M.D. In July 2009, our research article, “Effect of acute alcohol use on the lethality of suicide attempts in patients with mood disorders” was published in the Journal of Psychiatric Research (1). We hypothesized that acute alcohol intoxication is associated with more lethal suicide attempts. To test this hypothesis, we examined the effect […]