Leo Sher, M.D. A research report, “Cognitive and emotional impairments underpinning suicidal activity in patients with mood disorders: An fMRI study” has been published in Acta Psychiatrica Scandinavica online ahead of print (1). The authors sought to determine the nature of neural responses to an emotional-cognitive task in patients with suicidal activity. The Columbia Suicide […]
Leo Sher, M.D. A research report, “The effects of dietary improvement on symptoms of depression and anxiety: a meta-analysis of randomized controlled trials” has been published in Psychosomatic Medicine online ahead of print (1). The authors conducted a systematic review and meta-analysis examining effects of dietary interventions on symptoms of depression and anxiety. Twenty-six papers […]
Leo Sher, M.D. A research paper, “Patterns of altered regional brain glucose metabolism in borderline personality disorder and bipolar II disorder” has been published in Acta Psychiatrica Scandinavica online ahead of print (1). The authors examined brain glucose metabolism in patients with borderline personality disorder, in patients with bipolar II disorder, and healthy controls. In […]
Leo Sher, M.D. A research report, “Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models” is published in the January 2019 issue of Nature Medicine (1). Irisin is a myokine released into the circulation during physical exercise and is capable of stimulating adipocyte browning and thermogenesis in mice and humans. Irisin is cleaved […]
Leo Sher, M.D. A research article, “Leaky gut biomarkers in depression and suicidal behavior” has recently been published in Acta Psychiatrica Scandinavica online ahead of print (1). Researchers examined plasma levels of gut permeability markers in patients with a recent suicide attempt, major depressive disorder (MDD) subjects with no history of a suicide attempt, and […]
Leo Sher, M.D. A research report, “The association of religiosity with suicidal ideation and suicide attempts in the United Kingdom” has recently been published in Acta Psychiatrica Scandinavica online ahead of print (1). The authors used cross‐sectional data from 7403 people who participated in the 2007 Adult Psychiatric Morbidity Survey (APMS). The association between religiosity […]
Hilario Blasco-Fontecilla, M.D., Ph.D., Paula Artieda-Urrutia, M.D., Ph.D., Jose de Leon, M.D. Our research article, “A proposal for using the ratio of attempted to completed suicides across several countries worldwide” has recently been published in Epidemiology and Psychiatric Sciences online ahead of print (1). The rates of completed suicide (CS) are available for most developed countries worldwide. […]
Leo Sher, M.D. A scholarly article, “Association of testosterone treatment with alleviation of depressive symptoms in men: A systematic review and meta-analysis” has been published in JAMA Psychiatry online ahead of print (1). The authors examined the association of testosterone treatment with alleviation of depressive symptoms in men. The authors also examined effects of testosterone […]
Leo Sher, M.D. Our research report, “Gender differences and similarities in aggression, suicidal behaviour, and psychiatric comorbidity in borderline personality disorder” has been published in Acta Psychiatrica Scandinavica online ahead of print (1). We examined gender differences and similarities in aggression, impulsivity, suicidal behaviour, and psychiatric comorbidity in men and women with borderline personality disorder […]
Leo Sher, M.D. A seminal research work, “Amisulpride and olanzapine followed by open-label treatment with clozapine in first-episode schizophrenia and schizophreniform disorder (OPTiMiSE): a three-phase switching study” has recently been published in Lancet Psychiatry (1). A large international research group led by Professor René S. Kahn examined whether switching antipsychotic medications or early use of […]
