Leo Sher, M.D. A research report, “Parents’ perceptions of internalizing and externalizing features in childhood OCD” has been published in Child Psychiatry & Human Development online ahead of print (1). The authors of the study sought to show that parents perceive both internalizing and externalizing behaviors in childhood obsessive-compulsive disorder (OCD) by examining the factor […]
Leo Sher, M.D. A research paper, “Geographic proximity is associated with transmission of suicidal behavior among siblings” has been published in Acta Psychiatrica Scandinavica online ahead of print (1). The authors examined the role of “contagion”, or social transmission, in the risk of suicidal behavior among siblings. They employed Swedish national registry data to empirically […]
Leo Sher, M.D. A research report, “Effect of altitude on veteran suicide rates” has been published in High Altitude Medicine & Biology online ahead of print (1). Researchers from Salt Lake City, Utah, examined the relationship between veteran state-level suicide rates and altitude, including firearm-related and nonfirearm-related suicides. The authors extracted data related to state […]
Leo Sher, M.D. A research paper, “Divalproex and its effect on suicide risk in bipolar disorder: A systematic review and meta-analysis of multinational observational studies” has recently been published in the Journal of Affective Disorders (1). In general, studies on the effect of divalproex on suicide risk in patients with bipolar disorder have produced conflicting […]
Leo Sher, M.D. Three days ago, a research report, “Conventional and genetic evidence on alcohol and vascular disease aetiology: a prospective study of 500000 men and women in China” was published in The Lancet online ahead of print (1). Using data from a nationwide prospective study in China, researchers investigated the relationships between alcohol and […]
Leo Sher, M.D. A research report, “Cognitive and emotional impairments underpinning suicidal activity in patients with mood disorders: An fMRI study” has been published in Acta Psychiatrica Scandinavica online ahead of print (1). The authors sought to determine the nature of neural responses to an emotional-cognitive task in patients with suicidal activity. The Columbia Suicide […]
Leo Sher, M.D. A research report, “The effects of dietary improvement on symptoms of depression and anxiety: a meta-analysis of randomized controlled trials” has been published in Psychosomatic Medicine online ahead of print (1). The authors conducted a systematic review and meta-analysis examining effects of dietary interventions on symptoms of depression and anxiety. Twenty-six papers […]
Leo Sher, M.D. A research paper, “Patterns of altered regional brain glucose metabolism in borderline personality disorder and bipolar II disorder” has been published in Acta Psychiatrica Scandinavica online ahead of print (1). The authors examined brain glucose metabolism in patients with borderline personality disorder, in patients with bipolar II disorder, and healthy controls. In […]
Leo Sher, M.D. A research report, “Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models” is published in the January 2019 issue of Nature Medicine (1). Irisin is a myokine released into the circulation during physical exercise and is capable of stimulating adipocyte browning and thermogenesis in mice and humans. Irisin is cleaved […]
Leo Sher, M.D. A research article, “Leaky gut biomarkers in depression and suicidal behavior” has recently been published in Acta Psychiatrica Scandinavica online ahead of print (1). Researchers examined plasma levels of gut permeability markers in patients with a recent suicide attempt, major depressive disorder (MDD) subjects with no history of a suicide attempt, and […]
