Ros LT. Bratisl Lek Listy. 2008;109(10):459-60. Department of Neurosurgery, Central University Teaching Hospital with Policlinic, Armed Forces School of Medicine, Independent Public Health Care Institution, Warszawa, Poland.

The authors regard gambling as addiction. A detailed psychiatric examination revealed the obsessive-compulsive syndrome in the patient. The authors treated the patient systematically using the individual psychotherapy and sertraline from low doses up to the maximal dose (i.e., about 200 mg daily). A complete remission of the obsessive-compulsive syndrome was achieved.

A number of indirect proofs demonstrate a significant role of sertraline in the etiology of the obsessive-compulsive syndrome. The most important evidence is the effectiveness of the drugs from the group of selective inhibitors of serotonin central reuptake (SI-SHT) in the treatment of the obsessive-compulsive syndrome. Sertraline is safe and effective in the treatment of obsessive-compulsive syndrome (Ref. 7).