Chronic traumatic encephalopathy in an Iraqi war veteran with posttraumatic stress disorder who committed suicide.

Omalu B, Hammers JL, Bailes J, Hamilton RL, Kamboh MI, Webster G, Fitzsimmons RP.Neurosurg Focus. 2011 Nov;31(5):E3. AbstractFollowing his discovery of chronic traumatic encephalopathy (CTE) in football players in 2002, Dr. Bennet Omalu hypothesized that posttraumatic stress disorder (PTSD) in military veterans may belong to the CTE spectrum of diseases. The CTE surveillance at the […]

The antidepressant hyperforin increases the phosphorylation of CREB and the expression of TrkB in a tissue-specific manner.

Gibon J, Deloulme JC, Chevallier T, Ladevèze E, Abrous DN, Bouron A.Int J Neuropsychopharmacol. 2012 Jan 9:1-10. [Epub ahead of print] AbstractHyperforin is one of the main bioactive compounds that underlie the antidepressant actions of the medicinal plant Hypericum perforatum (St. John’s wort). However, the effects of a chronic hyperforin treatment on brain cells remains […]

Serum brain-derived neurotrophic factor level in relation to illness severity and episode duration in patients with major depression.

Birkenhäger TK, Geldermans S, Van den Broek WW, van Beveren N, Fekkes D.J Psychiatr Res. 2012 Jan 11. [Epub ahead of print] AbstractBACKGROUND: Since there are few data on the possible association between BDNF levels and characteristics of major depression, the present study assesses brain-derived neurotrophic factor (BDNF) levels in three drug-free patient samples, and […]

Cardiac Rehabilitation, Exercise Training, Cardiorespiratory Fitness, and Depression/Anxiety

Carl J Lavie, M.D., Arthur R. Menezes, M.D., Richard V. Milani, M.D.                                                                             We read with interest the recent study by Chamberlain and colleagues1 from Olmsted county demonstrating the association of depression and anxiety with hospitalizations for cardiovascular diseases (CVD), as well as the association of depression with increased all-cause mortality.  We have previously published on […]

Risk factors for cocaine-induced psychosis in cocaine-dependent patients

Roncero C, Daigre C, Gonzalvo B, Valero S, Castells X, Grau-López L, Eiroa-Orosa FJ, Casas M.Eur Psychiatry. 2011 Nov 23. [Epub ahead of print] Cocaine consumption can induce transient psychotic symptoms, expressed as paranoia or hallucinations. Cocaine induced psychosis (CIP) is common but not developed in all cases. This is the first European study on […]

Efficacy and safety of prolonged-release OROS methylphenidate in adults with attention deficit/hyperactivity disorder: A 13-week, randomized, double-blind, placebo-controlled, fixed-dose study

Casas M, Rösler M, Sandra Kooij JJ, Ginsberg Y, Ramos-Quiroga JA, Heger S, Berwaerts J, Dejonckheere J, van der Vorst E, Schäuble B.World J Biol Psychiatry. 2011 Nov 22. [Epub ahead of print] Objectives. Methylphenidate (MPH) is effective for adults with attention-deficit/hyperactivity disorder (ADHD). This study aimed to evaluate the efficacy and safety of OROS […]

Treatment of suicide attempters with bipolar disorder: a randomized clinical trial comparing lithium and valproate in the prevention of suicidal behavior

Oquendo MA, Galfalvy HC, Currier D, Grunebaum MF, Sher L, Sullivan GM, Burke AK, Harkavy-Friedman J, Sublette ME, Parsey RV, Mann JJ.Am J Psychiatry 2011 Oct;168(10):1050-6. OBJECTIVE: Bipolar disorder is associated with high risk for suicidal acts. Observational studies suggest a protective effect of lithium against suicidal behavior. However, testing this effect in randomized clinical […]

What can allostasis tell us about anabolic-androgenic steroid addiction?

Hildebrandt T, Yehuda R, Alfano L.Dev Psychopathol. 2011 Aug;23(3):907-19. Anabolic-androgenic steroids (AASs) are synthetic hormones used by individuals who want to look better or perform better in athletics and at the gym. Their use raises an interesting paradox in which drug use is associated with a number of health benefits, but also the possibility of […]

A new article on suicide in the military

Leo Sher, M.D. The article, “Death in Uniform” written by William Glenn, a Canadian journalist has been published in the “Canada’s Occupational Health and Safety Magazine” (1). The author writes about suicide among Canadian military veterans. He notes that “Age-specific analyses showed male veterans aged 16 to 44 were about one and a half times […]

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