CASIRIVIMAB and IMDEVIMAB {REGEN-COV}: 101 …Regeneron Pharmaceuticals’ monoclonal antibodies: a rescue pharmacotherapy for COVID-19…

Aya Allam, M.D., Steven Lippmann, M.D. Besides all the pandemic talk these days, we hear lots about coronavirus treatment with monoclonal antibodies. There are many of them. What is the big deal? Casirivimab and imdevimab are two monoclonal antibodies synthesized by the pharmaceutical company Regeneron, brand-named REGEN-COV. These dual proteins are a monoclonal antibodies intervention […]

Clinical characteristics and psychiatric comorbidities in veterans with schizophrenia with or without suicidality

Leo Sher, M.D. Our research report, “Clinical features and psychiatric comorbidities in military veterans with schizophrenia with or without suicidality” is published in the November 2021 issue of the Journal of Psychiatric Research (1). There is a need to increase our understanding of what elevates suicide risk in veterans with schizophrenia as a first step […]

Treatment of suicide attempters with bipolar disorder: a randomized clinical trial

Leo Sher, M.D. Our research report, “Treatment of suicide attempters with bipolar disorder: a randomized clinical trial comparing lithium and valproate in the prevention of suicidal behavior” was published in the October 2011 issue of the American Journal of Psychiatry (1). In our double-blind, randomized, parallel-group study, we tested the hypothesis that lithium offers bipolar […]

Changes in suicide mortality during the COVID-19 pandemic

Leo Sher, M.D. A research article, “Changes in suicide mortality of Hungary during the first year of the COVID-19 pandemic” has been published in Orvosi Hetilap, a Hungarian medical journal (1). The authors compared the observed number of suicides during the COVID-19 pandemic in March–December 2020 with the expected numbers which were calculated based on […]

The Nobel Prize in Physiology or Medicine 2021

Leo Sher, M.D. American scientists David Julius and Ardem Patapoutian were awarded the 2021 Nobel Prize in Physiology or Medicine for their discoveries of receptors for temperature and touch (1). The Nobel Committee states that “David Julius utilized capsaicin, a pungent compound from chili peppers that induces a burning sensation, to identify a sensor in […]

Cerebrospinal fluid monoamine metabolite levels and lethality of suicide attempts in patients with bipolar disorder: a prospective study

Leo Sher, M.D. Our research work, “A prospective study of the association of cerebrospinal fluid monoamine metabolite levels with lethality of suicide attempts in patients with bipolar disorder” was published 15 years ago in the October 2006 issue of Bipolar Disorders (1). We examined the relation between CSF 5-hydroxyindolacetic acid (5-HIAA), homovanillic acid (HVA), and […]

2021 National Veteran Suicide Prevention Annual Report

Leo Sher, M.D. The Office of Mental Health and Suicide Prevention of the U.S. Department of Veterans Affairs recently published the 2021 National Veteran Suicide Prevention Annual Report (1). This report provides information from 2001 through 2019, while recent prior reports included data from 2005 forward. Also, this report includes the most current data and […]

Ivermectin: 101

Gurpreet Singh Guliani, M.D., Steven Lippmann, M.D. We have been hearing a lot about ivermectin these days. You too? Well, ivermectin has long been established as a veterinary medication to treat animals with many different types of parasitic infections; useful there, it has been around for a while without fanfare. Ivermectin is also approved for […]

Coronavirus and Alzheimer’s disease – trust in FDA Vaccinations and Aducanumab

Aya Allam, M.D., Steven Lippmann, M.D. Now in our second year of a coronavirus pandemic, the Food and Drug Administration (FDA) is approving COVID-19 vaccines. They are well researched, proven safe, currently effective, and already utilized by millions of people. Trust in the FDA as a medical authority enhances their recommendations for getting immunized. Similarly, […]

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