Vinod KY, Hungund BL. Life Sci. 2005 Aug 19;77(14):1569-83. Several natural lipids have emerged as candidate modulators of central nervous system (CNS) functions. Fatty acid amides and their coupled signaling pathways are known to regulate several physiological and behavioral processes. Recent studies from our laboratory and others also have implicated endogenous marijuana-like brain constituents, endocannabinoids […]

Choi IG, Son HG, Yang BH, Kim SH, Lee JS, Chai YG, Son BK, Kee BS, Park BL, Kim LH, Choi YH, Shin HD. Hum Mutat. 2005 Sep;26(3):224-34. Alcoholism is a multifactorial and polygenic disorder involving complex gene-to-gene and gene-to-environment interactions. Alcohol metabolism is one of the biological determinants that could significantly be influenced by […]

Curtis D, Knight J, Sham PC. Psychiatr Genet. 2005 Sep;15(3):181-187 OBJECTIVE: Although LOD score methods have been applied to diseases with complex modes of inheritance, linkage analysis of quantitative traits has tended to rely on non-parametric methods based on regression or variance components analysis. Here, we describe a new method for LOD score analysis of […]

Kohnke MD, Batra A, Kolb W, Kohnke AM, Lutz U, Schick S, Gaertner I. Alcohol Alcohol. 2005 Sep-Oct;40(5):339-42. AIMS: It was investigated whether the allele A9 of the dopamine transporter gene (DAT1; SLC6A3) is associated with alcoholism, delirium tremens (DT), alcohol withdrawal seizures (AWS), or the daily alcohol intake.

Kiefer F, Jahn H, Otte C, Demiralay C, Wolf K, Wiedemann K. J Psychiatr Res. 2005 Sep;39(5):545-551. The appetite regulating peptide leptin has recently been associated with craving for alcohol and lifetime ethanol intake. However, effects of anti- craving drugs on leptin have not been studied until now.