Leo Sher, M.D. Our research report, “Moral objections to suicide and suicidal ideation among mood disordered Whites, Blacks, and Hispanics” was published in the January 2009 issue of the Journal of Psychiatric Research (1). We examined the moral objections to suicide and suicidal ideation of White, Black, and Hispanic individuals with mood disorders. In all, […]
Leo Sher, M.D. Ten years ago, our research paper, “Depressed patients with co-occurring alcohol use disorders: a unique patient population” was published in the Journal of Clinical Psychiatry (1). We compared depressed subjects with and without co-occurring alcohol use disorder with respect to demographic and clinical parameters. 505 individuals were enrolled in the study. 318 […]
Leo Sher, M.D. Ten years ago, our research paper, “Serotonergic responses in depressed patients with or without a history of alcohol use disorders and healthy controls” was published in the September 2008 issue of European Neuropsychopharmacology (1). We compared serotonin function in major depressive disorder with co-occurring alcohol use disorder, major depressive disorder without co-occurring […]
Leo Sher, M.D. Ten years ago, a seminal research report, “Effectiveness of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: an open randomised clinical trial” was published in a 2008 issue of The Lancet (1). A large international group of research collaborators led by Professor Rene S. Kahn compared the effectiveness of second-generation antipsychotic drugs […]
Leo Sher, M.D. Ten years ago, a research report, “Twenty-four hour plasma cortisol and adrenocorticotropic hormone in Gulf War Veterans: Relationships to posttraumatic stress disorder and health symptoms” was published (1). The paper was published in a November 2007 issue of Biological Psychiatry (1). The authors examined the baseline functioning of the hypothalamic-pituitary-adrenal axis (HPA) […]
Leo Sher, M.D. About 10 years ago, we published a research report, “Triggers for suicidal behavior in depressed older adolescents and young adults: Do alcohol use disorders make a difference?” (1). The article was published in a 2007 issue of the International Journal of Adolescent Medicine and Health. We compared demographic and clinical features of […]
Leo Sher, M.D. Our research article, “CSF monoamine metabolites and lethality of suicide attempts in depressed patients with alcohol dependence” was published 10 years ago in a 2007 issue of “European Neuropsychopharmacology” (1). Monoaminergic abnormalities have been implicated in the pathophysiology of depression, alcohol use disorder, and suicidal behavior. We examined the relationship of cerebrospinal […]
Leo Sher, M.D. Our research report, “Positron emission tomography study of regional brain metabolic responses to a serotonergic challenge in major depressive disorder with and without comorbid lifetime alcohol dependence” was published in the September 2007 issue of European Neuropsychopharmacology (1). It was the first study comparing the regional glucose metabolic rate (rCMRglu) responses to […]
