This book describes the neurobiological mechanisms of alcohol abuse and dependence including the role of serotonergeic, dopaminergic, noradrenergic, and hypothalamic-piturary adrenal systems in alcohol use disorders and the results of neuroimaging studies are presented. The neurobiology of comorbidity of alcohol use disorders with other psychiatric disorders is also discussed. Research on the neurobiology of alcohol abuse and dependence is very important. Therefore, this book will be of interest to biomedical researchers, physicians, and other clinicians, students, and anyone who is interested in the mechanisms of addictive disorders.

 

Publisher: Nova Science Publishers

Editor: Leo Sher, M.D.

Contributors:

Norberto Bilbeny, M.D., Garbil Pharma Investigación Chile, Santiago, Chile

Selfa Contreras, Pharm.D., Garbil Pharma Investigación Chile, Santiago, Chile

Randall L. Davis, Ph.D., Neuroinflammation Research Laboratory, Department of Pharmacology/Physiology, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA

Nicholas Floreani, B.S., Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA

María Font, Ph. D., Pharm.D., D.Biol.Sci., Unit of Molecular Modelling, Faculty of Pharmacy, University of Navarra, Pamplona, Spain

Hernán Garcia, Pharm.D., Garbil Pharma Investigación Chile, Santiago, Chile

Christoph von der Goltz, M.D., University of Heidelberg, Dept. of Addictive Behaviour and Addiction Medicine, Central Institute of Mental Health (CIMH), Mannheim, Germany

James Haorah, Ph.D., Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA

Andreas Heinz, M.D., Department of Psychiatry and Psychotherapy of the Charité – University Medical Center, Campus Charité Mitte, Berlin, Germany

Susumu Higuchi, M.D., Ph.D., National Hospital Organization Kurihama Alcoholism Center, Yokosuka, Kanagawa, Japan

George A. Kenna, Ph.D., R.Ph. Department of Psychiatry, Brown University, Providence, RI, and The Westerly Hospital, Westerly, RI, USA

Falk Kiefer, M.D., University of Heidelberg, Dept. of Addictive Behaviour and Addiction Medicine, Central Institute of Mental Health (CIMH), Mannheim, Germany

Thorsten Kienast, M.D., Department of Psychiatry and Psychotherapy of the Charité – University Medical Center, Campus Charité Mitte, Berlin, Germany

John H. Krystal, M.D., Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA

Nita Makhija, Ed.M., Department of Psychiatry, Columbia University, and New York State Psychiatric Institute, New York, NY, USA

Rosanna Mancinelli, Biol. Sci. D., Department of Environment and Primary Prevention, Istituto Superiore di Sanità, Roma, Italy

Ann M. Manzardo, Ph.D., Department of Psychiatry and Behavioral Sciences, University of Kansas Medical Center, Kansas City, KS, USA

Ezio Manzato, M.D.,Department of Addiction Medicine, Hospital “Chiarenzi” of Zevio, Verona, and Italian Society of Addiction Medicine (FeDerSerD), Milan, Italy

Sachio Matsushita, M.D., National Hospital Organization Kurihama Alcoholism Center, Yokosuka, Kanagawa, Japan

Milagros Méndez, Ph.D., Departamento de Neuroquímica, Subdirección de Investigaciones Clínicas, Instituto Nacional de Psiquiatría Ramón de la Fuente, México D.F., México

Jose Javier Miguel-Hidalgo, Ph.D., Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, MS, USA

Marcela Morales-Mulia, Ph.D., Departamento de Neuroquímica, Subdirección de Investigaciones Clínicas, Instituto Nacional de Psiquiatría Ramón de la Fuente, México D.F., México

Stephanie A. Morris, B.S., Department of Pharmaceutical Sciences, The University of Kentucky, Lexington, KY, USA

Felice Nava, M.D.,Department of Addiction Medicine, Hospital of Castelfranco Veneto, Treviso, and Italian Society of Addiction Medicine (FeDerSerD), Milan, Italy

Kimberly Nixon, Ph.D., Department of Pharmaceutical Sciences, The University of Kentucky, Lexington, KY, USA

Carlos Paeile, D.D.S., Garbil Pharma Investigación Chile, Santiago, Chile

Elizabeth C. Penick, Ph.D., Department of Psychiatry and Behavioral Sciences, University of Kansas Medical Center, Kansas City, KS, USA

Yuri Persidsky M.D., Ph.D., Departments of Pharmacology and Experimental Neuroscience, and Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA

Carmen Rasmussen, Ph.D., Department of Pediatrics, University of Alberta and Glenrose Rehabilitation Hospital, Edmonton, Alberta, Canada

Sungwon Roh, M.D., Ph.D., National Hospital Organization Kurihama Alcoholism Center, Yokosuka, Kanagawa, Japan

Gunter Schumann, M.D., Institute of Psychiatry, Kings College, London, UK

Leo Sher, M.D., Department of Psychiatry, Columbia University, and New York State Psychiatric Institute, New York, NY, USA

Peter J. Syapin, Ph.D., Alcohol and Brain Research Laboratory, Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, TX, USA

Roberta J. Ward, Ph.D., Biologie du Comportement, Université Catholique de Louvain, Louvain-la-Neuve, Belgium

Philippe De Witte, Ph.D., Biologie du Comportement, Université Catholique de Louvain, Louvain-la-Neuve, Belgium

Katy Wyper, B.Sc., Department of Pediatrics, University of Alberta and Glenrose Rehabilitation Hospital, Edmonton, Alberta, Canada