Leo Sher, M.D.

The research team led by Alexander Neumeister, MD, Associate Professor of Psychiatry at Mount Sinai School of Medicine and a Distinguished Guest of our website www.internetandpsychiatry.com (please, see the “Distinguished Guests” section of our website), found that a history of severe trauma exposure in patients with posttraumatic stress disorder (PTSD) and trauma exposed individuals without PTSD was associated with marked reductions in regional [¹¹C]P943 binding potential in the caudate, the amygdala, and the anterior cingulate cortex. Participant age at first trauma exposure was strongly associated with low [¹¹C]P943 binding potential.