Carl J Lavie, M.D., Arthur R. Menezes, M.D., Richard V. Milani, M.D.
We read with interest the recent study by Chamberlain and colleagues1 from Olmsted county demonstrating the association of depression and anxiety with hospitalizations for cardiovascular diseases (CVD), as well as the association of depression with increased all-cause mortality. We have previously published on the high prevalence of hostility and total psychosocial stress (PSS), as well as depression and anxiety, in patients with CVD.2-9 We agree that greater attention directed at depression, anxiety, and total PSS is needed in secondary, as well as primary, prevention of CVD.

Let's free our hearts from hatred. Let's give more. Let's expect less. Let's remember that life is not primarily a quest for pleasure, or a quest for power, but a quest for meaning...